|
KMID : 0361420150390020191
|
|
Journal of Korean Academy of Rehabilitation Medicine
2015 Volume.39 No. 2 p.191 ~ p.198
|
|
|
Effect of Enhanced External Counterpulsation and Cardiac Rehabilitation on Quality of Life, Plasma Nitric Oxide, Endothelin 1 and High Sensitive CRP in Patients With Coronary Artery Disease: A Pilot Study
|
|
Seyed Kazem Shakouri
Zeynab Razavi
Fariba Eslamian
Homayoun Sadeghi-Bazargani
Samad Ghaffari
Arash Babaei-Ghazani
|
|
|
Abstract
|
|
|
Objective: To investigate the effect of enhanced external counterpulsation (EECP) on plasma nitric oxide (NO), Endothelin 1 (ET1), high sensitive C-reactive protein (HSCRP) and quality of life (QoL) in patients with coronary artery disease (CAD).
Methods: We conducted a pilot randomized clinical trial in order to evaluate plasma NO, ET1, HSCRP and QoL before and after twenty sessions of EECP (group A) and cardiac rehabilitation (CR, group B) in 42 patients with CAD (21 in each group).
Results: Forty-two patients (33 male and 9 female) were included in the study. The mean age was 58.2±10 years. The mean HSCRP was 1.52±0.7 in the EECP group and it was reduced to 1.27±0.4 after intervention. The reduction in HSCRP was not statistically significant in EECP and CR groups with p=0.33 and p=0.27, respectively. There was not significant improvement of NO, ET1, and QoL in the EECP and CR groups shortly after therapy (p>0.05).
Conclusion: Although the short-term EECP treatment in CAD patients improved HSCRP, NO, ET1, and QoL compared with the baseline those improvements are not statistically significant. Further studies are necessary with large study groups and more sessions.
|
|
|
KEYWORD
|
|
|
Enhanced external counter pulsation (EECP), Coronary artery disease, Nitric oxide, Endothelins, High-sensitivity C-reactive protein
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|